D. Serafini et al – Ag-111 phantom images with Cerenkov Luminescence Imaging and digital autoradiography within the ISOLPHARM project
1 file(s) 1.79 MB
Download

2023

M. Tosato – Chromatographic separation of silver-111 from neutron-irradiated palladium target: toward direct labeling of radiotracers
1 file(s) 1.56 MB
Download
O.S. Khwairakpam et al., Resonant Laser Ionization and Fine-Structure Study of Silver in an Ablation Plume
1 file(s) 997.76 KB
Download
L. Morselli et al., Production and characterization of Ag-111 radioisotope for medical use in a TRIGA Mark II nuclear research reactor
1 file(s) 2.84 MB
Download
M. Tosato et al., Lights and Shadows on the Sourcing of Silver Radioisotopes for Targeted Imaging and Therapy of Cancer: Production Routes and Separation Methods
1 file(s) 6.80 MB
Download
A. Arzenton – Radiobiological model for β-emitter radiopharmaceutical therapy in dynamic cell cultures in the framework of the ISOLPHARM project
1 file(s) 407.66 KB
Download

2022

M. Tosato et al., Chelation of Theranostic Copper Radioisotopes with S-Rich Macrocycles: From Radiolabelling of Copper-64 to In Vivo Investigation
1 file(s) 3.77 MB
Download
M. Tosato et al., When ring makes the diﬀerence: coordination properties of Cu 2+ /Cu + complexes with sulfur-pendant polyazamacrocycles for radiopharmaceutical applications
1 file(s) 2.61 MB
Download
V. Benfante et al, A New Preclinical Decision Support System Based on PET Radiomics: A Preliminary Study on the Evaluation of an Innovative 64Cu-Labeled Chelator in Mouse Models
1 file(s) 28.78 MB
Download
O.S. Khwairakpam et al., Laser photo-ionization study of natAg using opto-galvanic signal at SPES offline laser lab
1 file(s) 439.00 KB
Download
E. Vettorato et al., A new production method of high specific activity radionuclides towards innovative radiopharmaceuticals: the ISOLPHARM project
1 file(s) 549.85 KB
Download
A. Zanini et al., Sucrose-based sol-gel synthesis of microporous titanium carbide as target material for the production of radioisotopes
1 file(s) 7.72 MB
Download

2021

M. Ballan et al. – Development of implantation substrates for the collection of radionuclides of medical interest produced via ISOL technique at INFN-LNL
1 file(s) 5.59 MB
Download
M. Tosato et al. Copper Coordination Chemistry of Sulfur Pendant Cyclen Derivatives: An Attempt to Hinder the Reductive-Induced Demetalation in 64/67 Cu Radiopharmaceuticals
1 file(s) 2.44 MB
Download
M. Verona et al. Preliminary Study of a 1,5-Benzodiazepine-Derivative Labelled with Indium-111 for CCK-2 Receptor Targeting
1 file(s) 4.39 MB
Download

2020

M. Tosato et al. Chemical purification of 111-Ag from isobaric impurity 111-Cd by solid phase extraction chromatography: a proof of concept study
1 file(s) 350.41 KB
Download
M. Tosato et al. Highly Stable Silver(I) Complexes with Cyclen-Based Ligands Bearing Sulfide Arms
1 file(s) 2.08 MB
Download
M. Ballan et al Preliminary evaluation of the production of non-carrier added 111-Ag as core of a therapeutic radiopharmaceutical in the framework of ISOLPHARM_Ag experiment
1 file(s) 6.28 MB
Download
V. Di Marco et al. pH-static titrations for kinetic studies of metal-ligand complex formation: The case example of the reaction between Strontium(II) and DOTA
1 file(s) 335.34 KB
Download
S. Corradetti, A. Andrighetto, The ISOLPHARM Project: Production of High Specific Activity Medical Radioisotopes at SPES, 2020
1 file(s) 779.38 KB
Download
M. Tosato et al., Toward novel sulphur-containing derivatives of tetraazacyclododecane: synthesis, acid–base properties, spectroscopic characterization, DFT calculations, and cadmium(II) complex formation in aqueous solution, 2020
1 file(s) 3.05 MB
Download

2019

A.Andrighetto et al., The ISOLPHARM project: ISOL-based production of radionuclides for medical applications, 2019
1 file(s) 871.56 KB
Download
A. Andrighetto et al. ISOLPHARM, a new production method of high specific activity beta-emitting radionuclides as radiopharmaceutical precursors
1 file(s) 164.97 KB
Download

2018

F.Borgna et al., Early Evaluation of Copper Radioisotope Production at ISOLPHARM, 2018
1 file(s) 7.95 MB
Download
A. Andrighetto et al. The ISOLPHARM project: A New ISOL production method of high specific activity beta-emitting radionuclides as radiopharmaceutical precursors
1 file(s) 1.59 MB
Download
A. Andrighetto et al. A Novel Methods FGor The Production Of Radionuclides Of Medical Interest With Accelerators
1 file(s) 475.40 KB
Download

2017

F.Borgna et al., A preliminary study for the production of high specific activity radionuclides for nuclear medicine obtained with the isotope separation on line technique, 2017
1 file(s) 1.72 MB
Download

Posters

2023

D. Serafini, A. Arzenton et al., The Resonant Ionization Laser Ion Source @ SPES-ISOLPHARM
1 file(s) 6.65 MB
Download

2022

O.S. Khwairakpam et al., Laser Photo-Ionization of natAg in the SPES offline laser lab, INFN-LNL (Application in the Radioactive Ion Beam facility)
1 file(s) 728.81 KB
Download

2021

L. Morselli et al. – The ISOLPHARM collaboration : a facility for the production and study of innovative radiopharmaceuticals
1 file(s) 4.30 MB
Download

2020

Nardella S. et al., Chemical purification of 111-Ag from isobaric impurity 111-Cd by solid phase extraction chromatography, VIII GICR National Congress, September 18 th, 19th 2020, Padova, Italy
1 file(s) 1.97 MB
Download
Verona M. et al., Radiolabeling and preliminary in vivo study of a small molecule-based ligand for CCK2 receptors targeting, VIII GICR National Congress, September 18 th, 19th 2020, Padova, Italy
1 file(s) 1,008.42 KB
Download
Ballan M. et al., Collection targets for the ISOLPHARM project, VIII GICR National Congress, September 18 th, 19th 2020, Padova, Italy
1 file(s) 1.14 MB
Download
Morselli L. et al., Study of 111-Ag production via the 110-Pd(n,γ) 111-Ag reaction, VIII GICR National Congress, September 18 th, 19th 2020, Padova, Italy
1 file(s) 520.40 KB
Download
Corradetti S. et al., The ISOLPHARM_EIRA INFN experiment, VIII GICR National Congress, September 18 th , 19 th 2020 Padova, Italy
1 file(s) 1.23 MB
Download

2019

Zangrando L. et al., ISOLPHARM_Ag Simulazioni Monte Carlo con Kubernetes, Workshop della commissione Calcolo dell’ INFN, LA Biodola, Isola d’Elba, 3-7 Giugno 2019
1 file(s) 370.60 KB
Download
Caeran M. et al., Progetto Isolpharm_Ag: Produzione di 111Ag e progettazione di radiofarmaci a scopo terapeutico, 59° Simposio AFI, Rimini, 5-7 Giugno 2019
1 file(s) 1.43 MB
Download
M.Tosato, MEDICIS-Promed Final Conference, Erice, 29-4 May 2019
1 file(s) 5.52 MB
Download
Corradetti S. et al., The ISOLPHARM Project: ISOL-based production of radioisotopes fo medical applications, Joint LIA COLL‐AGAIN, COPIGAL, and POLITA Workshop (French-Italian-Polish Collaborations) 5-7 March 2019 Heavy Ion Laboratory University of Warsaw, Warsaw, Poland
1 file(s) 6.34 MB
Download

2018

Ballan M. et al., Production target concepts for the SPES – ISOLPHARM project, EURISOL, Pisa, 2-4 Luglio 2018,
1 file(s) 1.61 MB
Download
Ferrari M. et al., ISOLPHARM: new ISOL-production method of high specific activity beta-emitting radionuclides as radiopharmaceutical precursors, RAD 2018, Ohrid, Macedonia (FYROM), 18th-22th June 2018
1 file(s) 6.25 MB
Download
Corradetti S. et al., Development of targets for the production of radionuclides at the ISOLPHARM project, VII GICR National Congress May 11 th , 12 th 2018 Ferrara, Italy
1 file(s) 2.08 MB
Download
Verona M. et al., Synthesis of small molecule-based ligands for active targeting of CCK2R for the ISOLPHARM-Ag project, VII GICR National Congress May 11 th , 12 th 2018 Ferrara, Italy
1 file(s) 853.92 KB
Download
Favaretto C. et al., Production of carrier-free copper radionuclides with the ISOLPHARM method for nuclear medicine, VII GICR National Congress May 11 th , 12 th 2018 Ferrara, Italy
1 file(s) 2.40 MB
Download
Borgna F. et al., ISOLPHARM_Ag project: production and purification of silver ion beams for 111Ag production, VII GICR National Congress – May 11th, 12th 2018 – Ferrara, Italy
1 file(s) 7.54 MB
Download
Ballan M. et al.,Target concepts for the production of radionuclides of medical interest for the ISOLPHARM Project, VII GICR National Congress – May 11 th , 12 th 2018 – Ferrara, Italy
1 file(s) 1.81 MB
Download

2016

D’Odorico G. et al., Synthesis and Characterization of Sodium Nonatitanate Ion Exchanger (Na4Ti9O20 ∙ xH2O) for 90Sr removal from 90Y, A.It.UN., Parma, Maggio 2016
1 file(s) 3.95 MB
Download
Todesco C. et al., Design of pharmaceutical process for the deposition and recovery of Iodine from an accelerated ion beam obtained with isotopes separation on-line method (ISOL), A.It.UN, Parma, Maggio 2016
1 file(s) 2.82 MB
Download
Vettorato E. et al., Chemical separation of Strontium from Yttrium for the preparation of high radionuclidic purity 90Y produced with the ISOL technique for innovative radiopharmaceuticals, A.It.UN., Parma, Maggio 2016
1 file(s) 3.44 MB
Download

2015

Borgna F. et al., Research and technological development of b- emitting radiopharmaceuticals produced with radioactive ion beams, 55° AFI Simposium, Rimini, 2015
1 file(s) 2.74 MB
Download

Ph.D. & Master Thesis

PhD Theses

2024

A. Arzenton – Towards 111Ag as a medical radionuclide: from production and laser photo-ionisation to cell dosimetry and radiation biophysics in the context of the ISOLPHARM project

1 file(s) 11.93 MB

Download

2023

L. Morselli – Production and Characterization of Ag-111 for radiopharmaceutical applications in the framework of the ISOLPHARM project

1 file(s) 123.59 MB

Download

2019

Ballan M., Development of targets for the production of radionuclides of medical interest according to the ISOL technique, XXXI series, 2019

1 file(s) 14.58 MB

Download

2018

Borgna F., Pharmaceutical development of the ISOL technique for the production of radionuclides and their applications in targeted radionuclide therapy, XXX series, 2018

1 file(s) 6.44 MB

Download

Master Degree Theses

2024

F. Nicente – Screening e sviluppo tecnologico di target di deposizione innovativi per la raccolta di radionuclidi medicali nell’ambito del progetto ISOLPHARM

1 file(s) 5.90 MB

Download

2023

V. Pavanello – Performance study of a novel 2D imaging beta detector for medical applications

1 file(s) 16.04 MB

Download

N. Zancopè – Analysis and interpretation of CLI and DRI images in view of a Ag-111 biodistribution experiment

1 file(s) 33.79 MB

Download

A. Leso – Study of DNA damage by beta radiation using Geant4-DNA in the context of the ISOLPHARM project

1 file(s) 12.98 MB

Download

E. Reniero – Cellular dosimetry using Geant4 in the context of the ISOLPHARM project

1 file(s) 19.30 MB

Download

2022

L. Compagno – Sviluppo e caratterizzazione di target di deposizione e validazione del sistema ISOLPHARM Radionuclide Implatation Station (IRIS) nell’ambito del progetto ISOLPHARM

1 file(s) 2.31 MB

Download

D. Serafini – Monte-Carlo simulations for medical images interpretation in the context of the ISOLPHARM project

1 file(s) 25.67 MB

Download

F. Dian – Sintesi di un nuovo chelante azamacrociclico con relativa caratterizzazione in vitro per la determinazione delle pKa

1 file(s) 2.89 MB

Download

G. Colombara – Sintesi e caratterizzazione di nuovi chelanti azamacrociclici rigidificati utilizzabili in terapia radiofarmaceutica

1 file(s) 2.25 MB

Download

F. Speziani – Liposomes engineering for tumor-selective delivery of radionuclides

1 file(s) 2.49 MB

Download

2021

G. Moretto – Formulazione e Screening di Sistemi Macromolecolari e Vescicolari per il Direzionamento Attivo di Radionuclidi Terapeutici nel Progetto ISOLPHARM

1 file(s) 2.67 MB

Download

G. De Pizzol – Sviluppo Tecnologico di nuovi Target di Deposizione di Radionuclidi per la Tecnica ISOL

1 file(s) 4.73 MB

Download

M. Pelosato – Complessi di Cu(II) e Cu(I) con Derivati Solforati di Poliazamacrocicli Aventi Interesse Radiofarmaceutico

1 file(s) 6.47 MB

Download

S. Franchi – Studio della Formazione di Complessi di Ag(I) e Cd(II) con Derivati Solforati di Poliazacicloalcani

1 file(s) 3.28 MB

Download

A. Arzenton – Monte Carlo based dosimetry using PET/CT and SPECT/CT imaging in radiopharmaceutical therapy in the context of the ISOLPHARM project

1 file(s) 3.70 MB

Download

Crocetta F. – Design of Cell-Laden Gelatin Methacryloyl Based Hydrogels For In Vitro Testing Of Radiopharmaceutical

1 file(s) 34.34 MB

Download

2020

Martini D., Progettazione e sviluppo di un sistema di raccolta e movimentazione di bersagli per la deposizione di isotopi radioattivi di interesse medico

1 file(s) 14.04 MB

Download

Berberi E., Studio della formazione di complessi tra Cu(II) e derivati del Tetraazaciclododecano di interesse radiofarmaceutico (progetto ISOLPHARM), A.A. 2019-20

1 file(s) 1.61 MB

Download

Abazi S., Sintesi e veicolazione di radiofarmaci nell’ambito del progetto ISOLPHARM, aventi Nastorazepide come direzionante, A.A. 2019-20

1 file(s) 2.08 MB

Download

Poloniato A., Formulazione e validazione di target per la deposizione di 111Ag nell’ambito del progetto ISOLPHARM, A.A. 2019-20

1 file(s) 17.68 MB

Please login to download

2019

Nardella S., Sviluppo di metodi di separazione di Ag(I) dal contaminante isobarico Cd(II) per la produzione di radionuclidi ad uso terapeutico, A.A. 2018-19

1 file(s) 3.72 MB

Download

Pedrolo C., Linker idrofilici condizionanti la farmacocinetica e la farmacodinamica di ligandi per radioisotopi nell’ambito del progetto ISOLPHARM, A.A. 2018-19

1 file(s) 2.78 MB

Download

Realdon F., Progetto ISOLPHARM: sintesi di chelanti bifunzionali per radionuclidi di interesse farmaceutico, A.A. 2018-19

1 file(s) 1.39 MB

Download

Sturaro N., Sviluppo tecnologico di un target secondario innovativo per la deposizione di radioisotopi ad uso medico e studio preliminare della ionizzazione di Tb nell’ambito del progetto ISOLPHARM, A.A. 2018-19

1 file(s) 4.83 MB

Download

Doro R., Studio della formazione di complessi di Argento(I), Cadmio(II) e Rame(II) con derivati tioeterei del 1,4,7,10-Tetraazaciclododecano per possibili applicazioni in medicina nucleare, A.A. 2018-19

1 file(s) 10.04 MB

Download

2018

Mengarelli D., Sviluppo di un target refrattario mesoporoso in carburo di titanio per applicazioni in fisica e medicina nucleare, A.A. 2017-18

1 file(s) 7.78 MB

Download

Caeran M., Progetto Isolpharm_Ag: Ionizzazione, deposizione e purificazione dell’ 111Ag per la produzione di radiofarmaci ad uso terapeutico, A.A. 2017-18

1 file(s) 23.86 MB

Download

Verona M., Sintesi e caratterizzazione di molecole per il targeting attivo sul recettore CCK2R, A.A. 2017-18

1 file(s) 1.45 MB

Download

Tosato M., Sintesi e studio termodinamico di nuovi possibili chelanti bifunzionali per la targeted radionuclide therapy con 111Ag (progetto Isolpharm_Ag), A.A. 2017-18

1 file(s) 7.71 MB

Download

Quaggiotto G., Progetto Isolpharm_Ag: Sviluppo tecnologico di un processo farmaceutico per la produzione di 111Ag e relativa purificazione, A.A. 2017-18

1 file(s) 3.08 MB

Download

2017

Pellizzola M., Ricerca di un metodo di purificazione dello 89Sr dal suo contaminante 89Y per lo sviluppo tecnologico di un radiofarmaco e ionizzazione dello 45Sc con la tecnologia Isotope Separation On-Line (ISOL)

1 file(s) 3.97 MB

Download

Favaretto C., Sviluppo tecnologico di un prototipo di generatore 90Sr/90Y e determinazione dell’efficienza di deposizione di 63Cu per radionuclidi prodotti con tecnologia ISOL, A.A. 2016-17

1 file(s) 23.32 MB

Download

2016

Vettorato E. Studio dello scambiatore ionico Nonatitanato per la purificazione di un radiofarmaco a base di 90Y dal contaminante 90Sr, prodotto con tecnologia ISOL, A.A. 2015-16

1 file(s) 4.47 MB

Download

Todesco C., Sviluppo di un processo farmaceutico per la produzione di 131I e 125I con tecnologia ISOL (Isotope Separation On-Line), AA. 2015-16

1 file(s) 8.59 MB

Download

D’Odorico G., Sviluppo preliminare di una preparazione radiofarmaceutica contenente 90YCl3 mediante tecnologia Isotope Separation On Line (ISOL), A.A. 2015-16

1 file(s) 5.85 MB

Download

2014

Borgna F., Potenzialità della tecnologia Isotope Separation On Line (ISOL) per la realizzazione di un radiofarmaco a base di 89Sr e preliminare sviluppo tecnologico della forma farmaceutica, A.A. 2013-14

1 file(s) 3.08 MB

Download

Bachelor Thesis

2024

C. Guerrini – Gestione amministrativa e finanziaria dei Laboratori Nazionali di Legnaro dell’INFN

1 file(s) 2.89 MB

Download

2022

G. Zago – Sviluppo di un rivelatore beta di grande area basato sui chip ALPIDE per il progetto ISOLPHARM

1 file(s) 5.12 MB

Download

M. Lijoi – Misure di biodistribuzione di molecole caricate a Cu-64 per l’esperimento ISOLPHARM

1 file(s) 1.33 MB

Download

2021

A. Leso – Studio dei radionuclidi prodotti al reattore LENA per il progetto ISOLPHARM_EIRA

1 file(s) 2.25 MB

Download

M. Panarelli – Misure di microdosimetria per il progetto ISOLPHARM_EIRA

1 file(s) 37.82 MB

Download

S. Sughi – Modellazione della produzione del radioisotopo Ag-111 a scopo medico in un reattore nucleare

1 file(s) 1.82 MB

Download

C. Pantouvakis – Caratterizzazione e primi test con il rivelatore gamma HPGe per la misura della produzione di Ag-111 nel progetto ISOLPHARM di produzione innovativa di radiofarmaci

1 file(s) 4.22 MB

Download

D. Pavone – Simulazione del sistema spettroscopico di misura della produzione di Ag-111 nel progetto ISOLPHARM di produzione innovativa di radiofarmaci

1 file(s) 12.00 KB

Download

2019

A. Arzenton – Studio dell’attività dei radionuclidi prodotti dal bersaglio SPES-ISOLPHARM

1 file(s) 1.20 MB

Download

Meetings

ISOLPHARM_ADMIRAL meetings (2023-25)

General meetings

1. ISOLPHARM_ADMIRAL Kick-off Meeting, 21 Dec 2022

2. ISOLPHARM_ADMIRAL Annual Meeting, 21 Dec 2023

3. ISOLPHARM_ADMIRAL Annual Meeting, 12 Dec 2024

Work Package 1 meetings

1. Work Package 1 meeting, 06 Mar 2023

2. Work Package 1 meeting, 14 May 2024

Work Package 2 meetings

1. Work Package 2 & 4 meeting, 29 May 2023

2. Work Package 2 & 4 meeting, 20 Jun 2024

Work Package 3 meetings

1. Work Package 3 meeting, 20 Jun 2023

2. Work Package 3 meeting, 04 Jun 2024

Work Package 4 meetings

1. Work Package 2 & 4 meeting, 29 May 2023

2. Work Package 2 & 4 meeting, 20 Jun 2024

ISOLPHARM_EIRA meetings (2020-22)

General meetings

1. ISOLPHARM_EIRA Kick-off Meeting, 29 Nov 2019

2. Plenary meeting – End 2020, 14 Dec 2020

3. Plenary meeting – End 2021, 16 Dec 2021

4. Plenary meeting – End 2022, 21 Dec 2022

Task 1 meetings

1. Task 1 meeting, 06 Apr 2020

2. Task 1 meeting, 15 Jul 2020

3. Task 1 meeting, 22 Apr 2021

4. Task 1 meeting, 21 Oct 2021

5. Task 1 meeting, 12 Jul 2022

Task 2 meetings

1. Task 2 meeting, 24 Apr 2020

2. Task 2 meeting, 30 Jul 2020

3. Task 2 meeting, 29 Mar 2021

4. Task 2 meeting, 19 Oct 2021

5. Task 2 meeting, 18 Jul 2022

Task 3 meetings

1. Task 3 meeting, 06 Feb 2020

2. Task 3 meeting, 29 Jul 2020

3. Task 3 meeting, 12 Apr 2021

4. Task 3 meeting, 26 Oct 2021

5. Task 3 meeting, 22 Jul 2022

ISOLPHARM_Ag meetings (2018-19)

General meetings

1. ISOLPHARM_Ag Kick-off Meeting, 12 Feb 2018

2. Plenary meeting – End 2018, 26 Nov 2018

3. Plenary meeting – End 2019, 29 Nov 2019

Task 1 meetings

1. Task 1 meeting, 05 Dec 2017

2. Task 1 meeting, 28 Mar 2018

3. Task 1 meeting, 30 May 2018

4. Task 1 meeting, 12 Jul 2018

5. Task 1 meeting, 19 Oct 2018

6. Task 1 meeting, 16 Mar 2019

Task 2 meetings

1. Task 2 meeting, 29 Mar 2018

2. Task 2 meeting, 08 Jun 2018

3. Task 2 meeting, 18 Feb 2019

Task 3 meetings

1. Task 3 meeting, 03 Apr 2018

2. Task 3 meeting, 26 Jun 2018

3. Task 3 meeting, 27 Feb 2019

Meetings with students

2021-04-21 – Isolpharm Meeting

1 file(s) 80.27 MB

Download

2019-10-18 Isolpharm meeting

1 file(s) 10.33 MB

Download

Data

ISOLPHARM_ADMIRAL data: https://drive.google.com/drive/folders/1w_LMegVgiDjnNjKNP7VV47OKryYM3fFo

ISOLPHARM_EIRA data: https://drive.google.com/drive/folders/1Nu9MTytfqf7_AgviClFmL4S-WANEGYUj

C.F. 84001850589

email: isolpharm at lnl.infn.it

Accessibility

Isolpharm

Manage Consent

To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.

Functional Functional Always active

The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.

Preferences Preferences

The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.

Statistics Statistics

The technical storage or access that is used exclusively for statistical purposes. The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.

Marketing Marketing

The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.

View preferences

{title} {title} {title}